GRIN2C Antikörper (AA 43-242)

Produktnummer ABIN3042433

Produktdetails anti-GRIN2C Antikörper

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Bindungsspezifität: AA 43-242

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIN2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, NMDA 2C(GRIN2C) detection. Tested with WB in Human,Rat.

Kreuzreaktivität (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, NMDA 2C(GRIN2C) detection. Tested with WB in Human,Rat.
Gene Name: glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Protein Name: Glutamate receptor ionotropic, NMDA 2C

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NMDAR2C recombinant protein (Position: Q43-Q242). Human NMDAR2C shares 93% and 92.5% amino acid (aa) sequence identity with mouse and rat NMDAR2C, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for NMDAR2C is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu GRIN2C

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Andere Bezeichnung: GRIN2C (GRIN2C Produkte)

Synonyme: GRIN2C antikoerper, NMDAR2C antikoerper, il12rb2l antikoerper, il-12rb2.b antikoerper, nr2c antikoerper, GluN2C antikoerper, NR2C antikoerper, glutamate ionotropic receptor NMDA type subunit 2C antikoerper, interleukin 12 receptor, beta 2a, like antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2C S homeolog antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2C antikoerper, glutamate receptor, ionotropic, NMDA2C (epsilon 3) antikoerper, GRIN2C antikoerper, il12rb2l antikoerper, grin2c.S antikoerper, grin2c antikoerper, Grin2c antikoerper

Hintergrund: NMDAR2C, known as GRIN2C, is mapped to 17q25.1. Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.

Synonyms: GluN2C antibody|Glutamate [NMDA] receptor subunit epsilon-3 antibody|Glutamate Receptor Ionotropic N Methyl D Aspartate 2C antibody|Glutamate receptor ionotropic, NMDA 2C antibody|Glutamate receptor, ionotropic, N methyl D aspartate 2C antibody|Grin2c antibody|N Methly D Aspartate Receptor Channel Subunit Epsilon 3 antibody|N Methyl D Aspartate Receptor Subtype 2C antibody|N methyl D aspartate receptor subunit 2C antibody|N-methyl D-aspartate receptor subtype 2C antibody|NMDAR2C antibody|NMDE3_HUMAN antibody|NR2C antibody|OTTHUMP00000041930 antibody

Gen-ID: 2905

UniProt: Q14957

Pathways: Synaptic Membrane