GRIN2C Antikörper (Internal Region)

Produktnummer ABIN6263663

Produktdetails anti-GRIN2C Antikörper

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIN2C Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: NMDA epsilon 3 Antibody detects endogenous levels of total NMDA epsilon 3.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NMDA epsilon 3, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu GRIN2C

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Andere Bezeichnung: GRIN2C (GRIN2C Produkte)

Synonyme: GRIN2C antikoerper, NMDAR2C antikoerper, il12rb2l antikoerper, il-12rb2.b antikoerper, nr2c antikoerper, GluN2C antikoerper, NR2C antikoerper, glutamate ionotropic receptor NMDA type subunit 2C antikoerper, interleukin 12 receptor, beta 2a, like antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2C S homeolog antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2C antikoerper, glutamate receptor, ionotropic, NMDA2C (epsilon 3) antikoerper, GRIN2C antikoerper, il12rb2l antikoerper, grin2c.S antikoerper, grin2c antikoerper, Grin2c antikoerper

Hintergrund:

Description: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:26875626). Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable). Plays a role in regulating the balance between excitatory and inhibitory activity of pyramidal neurons in the prefrontal cortex. Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning (By similarity).

Gene: GRIN2C

Molekulargewicht: 134 kDa

Gen-ID: 2905

UniProt: Q14957

Pathways: Synaptic Membrane