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CD38 Antikörper (Biotin)

Reaktivität: Human FACS Wirt: Maus Monoclonal HIT2 Biotin

Produktnummer ABIN303555

Datenblatt (PDF)

Target Alle CD38 Antikörper anzeigen

CD38
Reaktivität
151

55

28

12

12

12

1
Human
Wirt
103

78

24

1
Maus
Passende Sekundärantikörper
Klonalität
137

65

2
Monoklonal
Konjugat
63

15

15

12

8

7

7

6

5

5

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD38 Antikörper ist konjugiert mit Biotin
Applikation
156

68

37

34

32

26

26

16

16

13

7

7

6

3

2

2

2

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

This antibody reacts with CD38 (T10), a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes, it is an antigenic marker of lymphoid cells.

Kreuzreaktivität (Details)

Species reactivity (tested):Human

Immunogen

Human thymocytes in foetus

Klon

HIT2

Isotyp

IgG1

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anti-CD38 antibody
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Reaktivität: Human FACS Wirt: Maus Monoclonal HIT2 PE-DyLight 594

anti-CD38 (AA 43-300) antibody
Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM28 unconjugated

Applikationshinweise

Flow Cytometry analysis: 1:500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target

CD38

Abstract

CD38 Produkte

Synonyme

T10 antikoerper, Cd38-rs1 antikoerper, cd38 antikoerper, ADPRC 1 antikoerper, cADPr hydrolase 1 antikoerper, CD38 molecule antikoerper, CD38 antigen antikoerper, CD38 molecule L homeolog antikoerper, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 antikoerper, CD38 antikoerper, Cd38 antikoerper, cd38.L antikoerper

Hintergrund

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1

Gen-ID

952

UniProt

P28907