SLC22A1 Antikörper (C-Term)

Produktnummer ABIN3032681

Produktdetails anti-SLC22A1 Antikörper

Target: SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC22A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human SLC22A1/OCT1 (RKAKPKENTIYLKVQTSE) was used as the immunogen for this OCT1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the OCT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the OCT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu SLC22A1

Target: SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))

Andere Bezeichnung: OCT1 (SLC22A1) (SLC22A1 Produkte)

Synonyme: SLC22A1 antikoerper, OCT1 antikoerper, HOCT1 antikoerper, oct1_cds antikoerper, Lx1 antikoerper, Oct1 antikoerper, Orct antikoerper, Orct1 antikoerper, Roct1 antikoerper, SLC22A2 antikoerper, solute carrier family 22 member 1 antikoerper, solute carrier family 22 (organic cation transporter), member 1 antikoerper, solute carrier family 22 member 2-like antikoerper, SLC22A1 antikoerper, Slc22a1 antikoerper, LOC421584 antikoerper

Hintergrund: Solute carrier family 22 (organic cation transporter) member 1, also called OCT1 is a protein that in humans is encoded by the SLC22A1 gene. This gene is mapped to 6q25.3. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene transports the polyamines spermine and spermidine. It also transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. This gene regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.

UniProt: O15245

Pathways: Hormone Transport