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SLC22A1 Produkte

(Solute Carrier Family 22 (Organic Cation Transporter), Member 1, SLC22A1)
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008].

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Ausgewählte SLC22A1 Kategorien

SLC22A1 Antikörper

High quality antibodies with extensive validation data.

SLC22A1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SLC22A1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SLC22A1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
ApplikationICC, IF, IP, IHC (p), WB
Validierungen
  • (1)
  • collections(4)
Kat. Nr.ABIN2856060
Menge100 μL
ReaktivitätHuman
ApplikationFACS, ELISA, WB
Validierungen
  • (3)
  • collections(2)
Kat. Nr.ABIN969400
Menge100 μL
ReaktivitätCow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
ApplikationIHC, WB
Validierungen
  • collections(3)
Kat. Nr.ABIN2776861
Menge100 μL

Empfohlene SLC22A1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman, Mouse
Analytical MethodQualitative Cell ELISA
Validierungen
Kat. Nr.ABIN1380889
Menge96 tests
ReaktivitätHuman, Mouse
Analytical MethodQualitative DNA-Binding ELISA
Validierungen
Kat. Nr.ABIN5648541
Menge96 tests

Empfohlene SLC22A1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätMouse
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3131351
Menge0.25 mg
ReaktivitätHuman
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3095212
Menge1 mg
ReaktivitätMouse
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3131352
Menge1 mg

Neueste Publikationen zu unseren SLC22A1 Produkten

Sekhar, Georgian, Sanderson, Vizcay-Barrena, Brown, Muresan, Fleck, Thomas: "Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB)." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173474, 2017 (PubMed). Von den Autoren verwendete Methode: Immunoelectron Microscopy (IEM) (Probematerial (Species): Mouse (Murine)).

Zhang, Boxberger, Hagenbuch: "Organic anion transporting polypeptide 1B3 can form homo- and hetero-oligomers." in: PLoS ONE, Vol. 12, Issue 6, pp. e0180257, 2017 (PubMed). (Probematerial (Species): Human).

Kim, Raffler, Lu, Lee, Abbey, Saleheen, Rabinowitz, Bennett, Hand, Brown, Rader: "Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport." in: American journal of human genetics, Vol. 101, Issue 4, pp. 489-502, 2017 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (IHC) (Probematerial (Species): Mouse (Murine)).

Andreev, Brosseau, Carmona, Mes-Masson, Ramotar: "The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin." in: Scientific reports, Vol. 6, pp. 20508, 2016 (PubMed). (Probematerial (Species): Human). Weitere Details: Western Blotting

He, Qi, Jia, Wang, Wang, Song, Fu, Li, Luo: "Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p." in: Cancer letters, Vol. 368, Issue 1, pp. 115-25, 2015 (PubMed).

Seitz, Stalmann, Dalila, Chen, Pojar, Dos Santos Pereira, Krätzner, Brockmöller, Tzvetkov: "Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1." in: Genome medicine, Vol. 7, Issue 1, pp. 56, 2015 (PubMed). (Probematerial (Species): Mouse (Murine)). Weitere Details: Immunocytochemistry,Western Blotting,Immunofluorescence

Liu, Yin, Barrett, Sheppard-Tillman, Li, Casey, Fang, Hynes, Ameri, Kelly: "Loss of Androgen-Regulated MicroRNA 1 Activates SRC and Promotes Prostate Cancer Bone Metastasis." in: Molecular and cellular biology, Vol. 35, Issue 11, pp. 1940-51, 2015 (PubMed). (Probematerial (Species): Mouse (Murine)). Weitere Details: Chromatin Immunoprecipitation

Kitano, Kino, Yamamoto, Takitani, Miyoshi, Ishida, Saito, Arima, Satoh: "Bioinformatics Data Mining Approach Suggests Coexpression of AGTPBP1 with an ALS-linked Gene C9orf72." in: Journal of central nervous system disease, Vol. 7, pp. 15-26, 2015 (PubMed).

Salomon, Muchitsch, Gausterer, Schwagerus, Huwer, Daum, Lehr, Ehrhardt: "The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier." in: Molecular pharmaceutics, Vol. 11, Issue 3, pp. 995-1006, 2014 (PubMed).

Boxberger, Hagenbuch, Lampe: "Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 6, pp. 990-5, 2014 (PubMed).

Synonyme und alternative Namen zu SLC22A1

solute carrier family 22 member 1 (SLC22A1), solute carrier family 22 (organic cation transporter), member 1 (Slc22a1), solute carrier family 22 member 1 (Slc22a1), solute carrier family 22 member 2-like (LOC421584), HOCT1, Lx1, OCT1, Oct1, oct1_cds, Orct, Orct1, Roct1, SLC22A1, SLC22A2

Gen-IDs für verschiedene Spezies

GENE ID SPEZIES
472177 Pan troglodytes
100027984 Monodelphis domestica
100412933 Callithrix jacchus
100436901 Pongo abelii
397049 Sus scrofa
100008659 Oryctolagus cuniculus
6580 Homo sapiens
484068 Canis lupus familiaris
519461 Bos taurus
20517 Mus musculus
24904 Rattus norvegicus
421584 Gallus gallus

Bezeichner auf Proteinebene für SLC22A1

  • solute carrier family 22 member 1
  • solute carrier family 22 (organic cation transporter), member 1
  • solute carrier family 22 member 1-like
  • pOCT1
  • organic cation transporter 1
  • mOCT1
  • solute carrier family 22, member 1
  • solute carrier family 22 (organic cation transporter), member 2
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