PRNP Antikörper (Middle Region)

Produktnummer ABIN3032303

Produktdetails anti-PRNP Antikörper

Target: PRNP (Prion Protein (PRNP))

Bindungsspezifität: Middle Region

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRNP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of mouse Prion protein (DWEDRYYRENMYRYPNQ) was used as the immunogen for this Prion protein antibody (100% rat homology).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Prion protein antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Prion protein antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu PRNP

Target: PRNP (Prion Protein (PRNP))

Andere Bezeichnung: Prion Protein (PrP) (PRNP Produkte)

Synonyme: ASCR antikoerper, AltPrP antikoerper, CD230 antikoerper, CJD antikoerper, GSS antikoerper, KURU antikoerper, PRIP antikoerper, PrP antikoerper, PrP27-30 antikoerper, PrP33-35C antikoerper, PrPc antikoerper, p27-30 antikoerper, Prn antikoerper, Prn-p antikoerper, prp antikoerper, cjd antikoerper, prion antikoerper, prp(c) antikoerper, MGC84114 antikoerper, PRP antikoerper, PRPC antikoerper, Prp antikoerper, SIP antikoerper, PRNP antikoerper, AA960666 antikoerper, AI325101 antikoerper, PrP antikoerper, PrPC antikoerper, PrPSc antikoerper, Prn-i antikoerper, Sinc antikoerper, prP27-30 antikoerper, prP33-35C antikoerper, PrP-1 antikoerper, PrP1 antikoerper, prnprs1 antikoerper, stPrP-1 antikoerper, zgc:123004 antikoerper, prion protein antikoerper, prion protein S homeolog antikoerper, prion protein b antikoerper, PRNP antikoerper, Prnp antikoerper, prnp.S antikoerper, prnpb antikoerper

Hintergrund: Prion protein, also known as CD230 and PRP, is encoded by the PRNP gene. The major prion protein is expressed in the brain and several other tissues. Expression is most predominant in the nervous system but occurs in many other tissues throughout the body. Puckett et al.(1991) identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20. PRNP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru.

UniProt: P04925

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation