Peroxiredoxin 5 Antikörper (C-Term)

Produktnummer ABIN3032191

Produktdetails anti-Peroxiredoxin 5 Antikörper

Target: Peroxiredoxin 5 (PRDX5)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human PRDX5 (DDSLVSIFGNRRLKRF) was used as the immunogen for this Peroxiredoxin 5 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Peroxiredoxin 5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Peroxiredoxin 5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Peroxiredoxin 5

Target: Peroxiredoxin 5 (PRDX5)

Abstract: PRDX5 Produkte

Synonyme: acr1 antikoerper, aoeb166 antikoerper, pmp20 antikoerper, prx-5 antikoerper, prx5 antikoerper, prxv antikoerper, sbbi10 antikoerper, GB16965 antikoerper, zgc:112318 antikoerper, PRDX5 antikoerper, CG 32920 antikoerper, CG 7217 antikoerper, CG32920 antikoerper, CG7217 antikoerper, Dmel\\CG7217 antikoerper, dPrx5 antikoerper, dprx5 antikoerper, ACR1 antikoerper, AOEB166 antikoerper, B166 antikoerper, PLP antikoerper, PMP20 antikoerper, PRDX6 antikoerper, PRXV antikoerper, prx-V antikoerper, AOPP antikoerper, Pmp20 antikoerper, Prdx6 antikoerper, PrxV antikoerper, Aoeb166 antikoerper, Prx V antikoerper, peroxiredoxin 5 L homeolog antikoerper, peroxiredoxin-5, mitochondrial antikoerper, peroxiredoxin 5 antikoerper, Peroxiredoxin 5 antikoerper, prdx5.L antikoerper, LOC552429 antikoerper, prdx5 antikoerper, PRDX5 antikoerper, Prx5 antikoerper, Prdx5 antikoerper

Hintergrund: Peroxiredoxin 5, also known as PRX5 and PRDX5, is a member of the peroxiredoxin family and may play an antioxidant protective role in various tissues under nonpathologic conditions and during inflammatory processes. PRDX5 displays mitochondrial presequence features and has 3 cysteines implicated in antioxidant activity and a C-terminal SQL peroxisomal targeting sequence. Northern blot analysis revealed ubiquitous expression of a 1.0-kb PRDX5 transcript in tissues and cell lines. Functional analysis showed that Peroxiredoxin 5 has antioxidant activity equivalent to that of CAT. While PRDX5 was localized to fibroblasts in normal tendon, it was localized to fibroblasts and endothelial cells in degenerative tendon. mRNA and protein levels increased at 12 hours, and the increase in PRDX5 expression correlated with reduced peroxide levels. Peroxiredoxin 5 plays a protective role against oxidative stress in human cartilage.

UniProt: P30044

Pathways: Cell RedoxHomeostasis