MCM3 Antikörper (N-Term)

Produktnummer ABIN3031805

Produktdetails anti-MCM3 Antikörper

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human MCM3 (REAQRDYLDFLDDEE) was used as the immunogen for this MCM3 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the MCM3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the MCM3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu MCM3

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Andere Bezeichnung: MCM3 (MCM3 Produkte)

Synonyme: HCC5 antikoerper, P1-MCM3 antikoerper, P1.h antikoerper, RLFB antikoerper, AL033361 antikoerper, C80350 antikoerper, Mcmd antikoerper, P1 antikoerper, p1.m antikoerper, cb32 antikoerper, chunp6867 antikoerper, wu:fa26g03 antikoerper, CG4206 antikoerper, DmMCM3 antikoerper, DmMcm3 antikoerper, DmeMCM3 antikoerper, Dmel\\CG4206 antikoerper, MCM3 antikoerper, McM3 antikoerper, Mcp-PCR2 antikoerper, PCR2 antikoerper, dMCM3 antikoerper, xmcm3 antikoerper, minichromosome maintenance complex component 3 antikoerper, MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) antikoerper, Minichromosome maintenance 3 antikoerper, minichromosome maintenance complex component 3 L homeolog antikoerper, MCM complex subunit Mcm3 antikoerper, MCM3 antikoerper, mcm3 antikoerper, Mcm3 antikoerper, mcm3.L antikoerper

Hintergrund: Minichromosome maintenance, S. cerevisiae, homolog of, 3, also called RLFB or P1 Protein, is a protein that in humans is encoded by the MCM3 gene. MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

UniProt: P25205

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA