MBD2 Antikörper (AA 159-411)
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- Target Alle MBD2 Antikörper anzeigen
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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Bindungsspezifität
- AA 159-411
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MBD2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Antigen affinity
- Immunogen
- Human partial recombinant protein (AA 159-411) was used as the immunogen for this MBD2 antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product MBD2 Primärantikörper
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- Applikationshinweise
- The stated application concentrations are suggested starting amounts. Titration of the MBD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the MBD2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
- Andere Bezeichnung
- MBD2 (MBD2 Produkte)
- Synonyme
- MBD2 antikoerper, DMTase antikoerper, NY-CO-41 antikoerper, MBD2a antikoerper, wu:fa97f06 antikoerper, zgc:111862 antikoerper, methyl-CpG binding domain protein 2 antikoerper, methyl-CpG binding domain protein 2 S homeolog antikoerper, MBD2 antikoerper, Mbd2 antikoerper, mbd2 antikoerper, mbd2.S antikoerper
- Hintergrund
- Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene. It is mapped to 18q21.2. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG-binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.
- Gen-ID
- 8932
- Pathways
- Chromatin Binding
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