IRF1 Antikörper (Middle Region)

Produktnummer ABIN3031414

Produktdetails anti-IRF1 Antikörper

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human Interferon regulatory factor 1 (YMQDLEVEQALTPAL) was used as the immunogen for this IRF1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the IRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the IRF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu IRF1

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Andere Bezeichnung: IRF1 (IRF1 Produkte)

Synonyme: irf1 antikoerper, zgc:136945 antikoerper, IRF1 antikoerper, irf11 antikoerper, zgc:103566 antikoerper, IRF-1 antikoerper, MAR antikoerper, AU020929 antikoerper, Irf-1 antikoerper, interferon regulatory factor 1 antikoerper, interferon regulatory factor 1a antikoerper, interferon regulatory factor 1b antikoerper, IRF1 antikoerper, irf1a antikoerper, irf1b antikoerper, Irf1 antikoerper

Hintergrund: Interferon regulatory factor 1, also known as MAR, is a protein that in humans is encoded by the IRF1 gene. IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. It also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor suppression.

UniProt: P10914

Pathways: Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagie