Glutamate Receptor 3 Antikörper (Middle Region)

Produktnummer ABIN3031068

Produktdetails anti-Glutamate Receptor 3 Antikörper

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human Glutamate receptor 3 (RKAGYWNEYERFVPFSDQQ) was used as the immunogen for this GLUR3 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the GLUR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the GLUR3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Andere Bezeichnung: GLUR3 (GRIA3 Produkte)

Synonyme: AMPA antikoerper, gria3 antikoerper, GRIN3A antikoerper, glur3b antikoerper, gria3.2 antikoerper, zfGRIA3[b] antikoerper, si:bz1o18.1 antikoerper, SI:zC231H1.1 antikoerper, si:zc140k5.3 antikoerper, GLUR3 antikoerper, GLUR-C antikoerper, GLUR3/C antikoerper, GRIA3 antikoerper, glur3 antikoerper, GluA3 antikoerper, GluR-3 antikoerper, GluR-C antikoerper, GluR-K3 antikoerper, GLUR-K3 antikoerper, GLURC antikoerper, MRX94 antikoerper, 2900064I19Rik antikoerper, Glur-3 antikoerper, Glur3 antikoerper, Gluralpha3 antikoerper, glutamate receptor, ionotropic, AMPA 3b antikoerper, glutamate ionotropic receptor AMPA type subunit 3 antikoerper, glutamate receptor, ionotropic, AMPA 3 antikoerper, glutamate receptor, ionotropic, AMPA 3 L homeolog antikoerper, glutamate receptor, ionotropic, AMPA3 (alpha 3) antikoerper, gria3b antikoerper, GRIA3 antikoerper, gria3 antikoerper, gria3.L antikoerper, Gria3 antikoerper

Hintergrund: Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. It is mapped to Xq25. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. In addition, GLUR3 has been shown to interact with GRIP1 and PICK1.

UniProt: P42263

Pathways: PI3K-Akt Signalweg, cAMP Metabolic Process, Synaptic Membrane