Decorin Antikörper (AA 31-359)

Produktnummer ABIN3030707

Produktdetails anti-Decorin Antikörper

Target: Decorin (DCN)

Bindungsspezifität: AA 31-359

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Decorin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 31-359) was used as the immunogen for this Decorin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Decorin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Decorin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Decorin

Target: Decorin (DCN)

Andere Bezeichnung: Decorin (DCN Produkte)

Synonyme: CSCD antikoerper, DSPG2 antikoerper, PG40 antikoerper, PGII antikoerper, PGS2 antikoerper, SLRR1B antikoerper, DC antikoerper, mDcn antikoerper, cscd antikoerper, dspg2 antikoerper, pg40 antikoerper, pgii antikoerper, pgs2 antikoerper, slrr1b antikoerper, decorin antikoerper, decorin L homeolog antikoerper, DCN antikoerper, Dcn antikoerper, dcn.L antikoerper, dcn antikoerper

Hintergrund: Decorin is a protein that in humans is encoded by the DCN gene. This gene is mapped to 12q21.3. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a protein core containing leucine repeats with a glycosaminoglycan (GAG) chain consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to Biglycan protein. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. And it also may play a role in epithelial/mesenchymal interactions during organ development and shaping. Decorin has been shown to have anti-tumorigenic properties in an experimental murine tumor model and is capable of suppressing the growth of various tumor cell lines.

Gen-ID: 1634

Pathways: Glycosaminoglycan Metabolic Process