Aromatase Antikörper (C-Term)

Produktnummer ABIN3030680

Produktdetails anti-Aromatase Antikörper

Target: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aromatase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Aromatase (KNMLEMIFTPRNSDRCLEH) was used as the immunogen for this Aromatase antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Aromatase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Aromatase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Aromatase

Target: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Andere Bezeichnung: Aromatase (CYP19A1 Produkte)

Synonyme: ARO antikoerper, ARO1 antikoerper, CPV1 antikoerper, CYAR antikoerper, CYP19 antikoerper, CYPXIX antikoerper, P-450AROM antikoerper, Aromatase antikoerper, Cyp19 antikoerper, Cyp19a antikoerper, p450arom antikoerper, P450 arom antikoerper, aro antikoerper, cyp19 antikoerper, cyp19a antikoerper, p450arom-A antikoerper, P450AROM antikoerper, Ar antikoerper, ArKO antikoerper, Int-5 antikoerper, Int5 antikoerper, CYP19P1 antikoerper, CYP19A1 antikoerper, CYP19a1 antikoerper, P450aromA antikoerper, ar1 antikoerper, cypXIX antikoerper, etID309862.18 antikoerper, zgc:136541 antikoerper, AroB antikoerper, CYP19a2 antikoerper, P450aromB antikoerper, cyp19b antikoerper, zgc:92614 antikoerper, cyp19a1 antikoerper, cytochrome P450 family 19 subfamily A member 1 antikoerper, cytochrome P450, family 19, subfamily a, polypeptide 1 antikoerper, cytochrome P450 family 19 subfamily A member 1 L homeolog antikoerper, aromatase antikoerper, cytochrome P450 aromatase antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1 antikoerper, cytochrome P450 19A1 antikoerper, cytochrome P450, family 17, subfamily A, polypeptide 1 antikoerper, cytochrome P450, family 19 antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1a antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1b antikoerper, cytochrome P450 19A1-like antikoerper, CYP19A1 antikoerper, Cyp19a1 antikoerper, cyp19a1.L antikoerper, SAV_2383 antikoerper, pfcyp19b-tstr antikoerper, CYP19 antikoerper, cyp19a1a antikoerper, cyp19a1b antikoerper, LOC101174651 antikoerper

Hintergrund: Aromatase is an enzyme responsible for a key step in the biosynthesis of estrogens. It is a member of the cytochrome P450 superfamily, which are monooxygenases that catalyze many reactions involved in steroidogenesis. In particular, aromatase is responsible for the aromatization of androgens into estrogens. The CYP19 gene spans at least 70 kb of genomic DNA and contains 10 exons. By in situ hybridization, the ARO gene is mapped to 15q21.1. The aromatase enzyme can be found in many tissues including gonads, brain, adipose tissue, placenta, blood vessels, skin, bone, and endometrium, as well as in tissue of endometriosis, uterine fibroids, breast cancer, and endometrial cancer. It is an important factor in sexual development. Some bodybuilders taking steroids also take antiaromatase supplements to prevent excess testosterone conversion into estrogens, which can cause gynecomastia.

UniProt: P11511

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis