Claudin 2 Antikörper (AA 38-230)

Produktnummer ABIN3030534

Produktdetails anti-Claudin 2 Antikörper

Target: Claudin 2 (CLDN2)

Bindungsspezifität: AA 38-230

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 38-230) was used as the immunogen for this Claudin 2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Claudin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Claudin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Claudin 2

Target: Claudin 2 (CLDN2)

Andere Bezeichnung: Claudin 2 (CLDN2 Produkte)

Synonyme: CLDN2 antikoerper, zgc:92260 antikoerper, AL022813 antikoerper, RGD1560247 antikoerper, claudin 2 antikoerper, CLDN2 antikoerper, cldn2 antikoerper, Cldn2 antikoerper

Hintergrund: Claudin 2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter.

Gen-ID: 9075

Pathways: Hepatitis C