CD82 Antikörper (AA 98-267)

Produktnummer ABIN3030428

Produktdetails anti-CD82 Antikörper

Target: CD82

Bindungsspezifität: AA 98-267

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD82 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Humanpartial recombinant protein (AA 98-267) was used as the immunogen for this CD82 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the CD82 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the CD82 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu CD82

Target: CD82

Andere Bezeichnung: CD82 (CD82 Produkte)

Synonyme: AA682076 antikoerper, AL023070 antikoerper, C33 antikoerper, IA4 antikoerper, Kai1 antikoerper, Tspan27 antikoerper, 4F9 antikoerper, GR15 antikoerper, KAI1 antikoerper, R2 antikoerper, SAR2 antikoerper, ST6 antikoerper, TSPAN27 antikoerper, CD82 antigen antikoerper, CD82 molecule antikoerper, Cd82 molecule antikoerper, Cd82 antikoerper, CD82 antikoerper

Hintergrund: Cluster of Differentiation 82, also called KAI1, is a protein that in humans encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression has been shown to be downregulated in tumor progression of human cancers and can be activated by < a href=../search_result.php?search_txt=p53>p53 through a consensus binding sequence in the promoter. The expression of CD82 appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma (ESCC). And overexpression can suppress tumor invasiveness and metastatic potential by inducing < a href=../search_result.php?search_txt=mmp9>MMP9 inactivation via upregulation of < a href=../search_result.php?search_txt=timp1>TIMP1.

Gen-ID: 3732

Pathways: p53 Signalweg