VEGFD Antikörper (Middle Region)

Produktnummer ABIN3030224

Produktdetails anti-VEGFD Antikörper

Target: VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VEGFD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human VEGFD (VIDEEWQRTQCSPRE) was used as the immunogen for this VEGFD antibody (100% homologous human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the VEGFD antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the VEGFD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu VEGFD

Target: VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))

Andere Bezeichnung: VEGFD (Figf Produkte)

Synonyme: FIGF antikoerper, vegfd antikoerper, vegf-d antikoerper, VEGFD antikoerper, AI325264 antikoerper, VEGF-D antikoerper, Vegfd antikoerper, Vegf-d antikoerper, vascular endothelial growth factor D antikoerper, Vascular endothelial growth factor D antikoerper, VEGFD antikoerper, vegfd antikoerper, vegfd.L antikoerper, Vegfd antikoerper

Hintergrund: C-fos induced growth factor(FIGF)(or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded by the FIGF gene. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor(PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. Analyzing by Northern blotting, Yamada et al.(1997) symbolized VEGFD, was expressed as a 2.2-kb transcript with highest expression in lung, heart, small intestine, and fetal lung, and lower levels in skeletal muscle, colon, and pancreas. And Achen et al.(1998) concluded that VEGFD was most closely related to VEGFC by virtue of the presence of N- and C-terminal extensions that were not found in other VEGF family members. Stacker et al.(2001) showed that VEGFD can induce tumor angiogenesis through VEGFR2 and tumor lymphangiogenesis through VEGFR3, whereas VEGF, which does not activate VEGFR3, induces only tumor angiogenesis.

UniProt: O43915

Pathways: RTK Signalweg