ADAMTS4 Antikörper (C-Term)

Produktnummer ABIN3029866

Produktdetails anti-ADAMTS4 Antikörper

Target: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAMTS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human ADAMTS4 (RRAQILEILRRRPWAGRK) was used as the immunogen for this ADAMTS4 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the ADAMTS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the ADAMTS4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu ADAMTS4

Target: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Andere Bezeichnung: ADAMTS4 (ADAMTS4 Produkte)

Synonyme: 3830423K05 antikoerper, ADAM-TS4 antikoerper, ADAMTS-2 antikoerper, ADMP-1 antikoerper, mKIAA0688 antikoerper, ADAMTS-4 antikoerper, ADAMTS4 antikoerper, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif 4 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif, 4 antikoerper, Adamts4 antikoerper, ADAMTS4 antikoerper

Hintergrund: A disintegrin and metalloproteinase with thrombospondin motifs 4' is an enzyme that in humans is encoded by the ADAMTS4 gene. It is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.

UniProt: O75173