IL2 Receptor beta Antikörper (AA 117-135)

Produktnummer ABIN3029732

Produktdetails anti-IL2 Receptor beta Antikörper

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Bindungsspezifität: AA 117-135

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL2 Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Amino acids 117-135 (RVMAIQDFKPFENLRLMAP-human) of the beta subunit were used as the immunogen for this IL-2 Receptor antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the IL-2 Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the IL-2 Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Andere Bezeichnung: IL-2 Receptor (Beta Subunit) (IL2RB Produkte)

Synonyme: IL2RB antikoerper, il-2rb antikoerper, CD122 antikoerper, IL15RB antikoerper, P70-75 antikoerper, IL2RBC antikoerper, IL-15Rbeta antikoerper, IL15Rbeta antikoerper, Il-2/15Rbeta antikoerper, Il-2Rbeta antikoerper, p70 antikoerper, interleukin 2 receptor subunit beta antikoerper, interleukin-2 receptor subunit beta antikoerper, interleukin 2 receptor, beta antikoerper, interleukin 2 receptor, beta chain antikoerper, IL2RB antikoerper, LOC510185 antikoerper, il2rb antikoerper, Il2rb antikoerper

Hintergrund: Interleukin 2 receptor beta, also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. IL-2 receptor is present in three forms with respect to binding ability to IL-2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL-2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.

UniProt: P14784

Pathways: JAK-STAT Signalweg, Growth Factor Binding