Tenascin R Antikörper (N-Term)

Produktnummer ABIN3029112

Produktdetails anti-Tenascin R Antikörper

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tenascin R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of mouse Tenascin-R (QTSDHESQVTFTHK) was used as the immunogen for this TNR antibody (100% rat homology).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the TNR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the TNR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Tenascin R

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Andere Bezeichnung: TNR (TNR Produkte)

Synonyme: TN-R antikoerper, J1-tenascin antikoerper, janusin antikoerper, restrictin antikoerper, J1NRM antikoerper, tenascin R antikoerper, TNR antikoerper, Tnr antikoerper

Hintergrund: Tenascin-R is a protein that in humans is encoded by the TNR gene. It is an extracellular matrix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (Hexabrachion), TNX (TNXB), and TNR. The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues. TNR has been detected predominantly in the central nervous system and is localized around motor neurons and on motor axons in the spinal cord, cerebellum, hippocampus, and olfactory bulb. It is suggested that Tenascin-R has a role in initiating the detachment of neuroblasts from tangential chains and in initiating radial migration of the cells.

UniProt: Q92752

Pathways: Regulation of Cell Size