Tenascin R Antikörper
Kurzübersicht für Tenascin R Antikörper (ABIN7075858)
Target
Alle Tenascin R (TNR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse TNR
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Applikationshinweise
- WB (H,M,R) 1:300-1:600
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))
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Andere Bezeichnung
- TNR
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Hintergrund
- TNR, also named as Restrictin and Janusin, belongs to the tenascin family. Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides, TNR inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2 (FAK) phosphorylation and cell detachment.
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Molekulargewicht
- 170 kDa
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Gen-ID
- 21960
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NCBI Accession
- NP_071707
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UniProt
- Q8BYI9
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Pathways
- Regulation of Cell Size
Target
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