CRHR2 Antikörper (N-Term)

Produktnummer ABIN3024521

Produktdetails anti-CRHR2 Antikörper

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRHR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A affinity chromatography

Immunogen: A recombinant protein fragment from the N-terminal portion of human CRHR2 was used as the immunogen for this antibody (1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Provided assay concentrations are suggestions only, CRHR2 antibody titration may be required for optimal results.

1. This antibody will detect the alpha (411 AA), beta (438 AA) and gamma (397 AA) isoforms of CRHR2.\. Western blot: 0.5-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CRHR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CRHR2

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Andere Bezeichnung: CRHR2 (CRHR2 Produkte)

Synonyme: CRF-RB antikoerper, CRF2 antikoerper, CRFR2 antikoerper, HM-CRF antikoerper, CRF-R2 antikoerper, CRFR2alpha antikoerper, CRFR2beta antikoerper, Crfr2 antikoerper, Crf2r antikoerper, CRH-R2 antikoerper, crhr2-A antikoerper, corticotropin releasing hormone receptor 2 antikoerper, corticotropin releasing hormone receptor 2 S homeolog antikoerper, CRHR2 antikoerper, Crhr2 antikoerper, crhr2.S antikoerper

Hintergrund: CHCR2, or Corticotropin releasing hormone receptor 2, is a receptor for CRH (corticotropin-releasing hormone), a neurotransmitter secreted by the hypothalamus in response to stress. There are three major isoforms of CHCR2: alpha, beta and gamma, differing in their N-terminus amino acid sequence. Isoform beta and gamma are expressed in the brain, with gamma expression highest in the septum and hippocampus, while alpha is expressed in the peripheral tissues of the brain.

Gen-ID: 1395

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour