MMP 9 Antikörper (AA 538-707)

Produktnummer ABIN3022900

Produktdetails anti-MMP 9 Antikörper

Target: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Bindungsspezifität: AA 538-707

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP 9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: KYWRFSEGRG SRPQGPFLIA DKWPALPRKL DSVFEERLSK KLFFFSGRQV WVYTGASVLG PRRLDKLGLG ADVAQVTGAL RSGRGKMLLF SGRRLWRFDV KAQMVDPRSA SEVDRMFPGV PLDTHDVFQY REKAYFCQDR FYWRVSSRSE LNQVDQVGYV TYDILQCPED

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 538-707 of human MMP9 (NP_004985.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-MMP 9 Antikörper (ABIN3022900)

Fu, Wang, Wu, Feng, Wang, Zhou, Ma, Wang: "HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer." in: Cell death & disease, Vol. 9, Issue 6, pp. 594, (2018) (PubMed).

Xing, Yu, Zhang, Luo, Lei, Huang, Lin, Huang, Huang, Nong, Zhou, Wei et al.: "Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial⁻Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR ..." in: International journal of molecular sciences, Vol. 19, Issue 6, (2018) (PubMed).

Doss, Samarpita, Ganesan, Rasool: "Ferulic acid, a dietary polyphenol suppresses osteoclast differentiation and bone erosion via the inhibition of RANKL dependent NF-κB signalling pathway." in: Life sciences, Vol. 207, pp. 284-295, (2018) (PubMed).

Xiong, Zhao, Lin, Yao, Huang, Yu, Dong, Xiao, Zhao, Cai et al.: "Phosphorylation of low density lipoprotein receptor-related protein 6 is involved in receptor for advanced glycation end product-mediated β-catenin stabilization in a toluene diisocyanate-induced ..." in: International immunopharmacology, Vol. 59, pp. 187-196, (2018) (PubMed).

Wang, Huang, Zhang, Hou, Liu, Chen, Zhu, Zhang: "Toosendanin suppresses oncogenic phenotypes of human gastric carcinoma SGC‑7901 cells partly via miR‑200a‑mediated downregulation of β-catenin pathway." in: International journal of oncology, Vol. 51, Issue 5, pp. 1563-1573, (2018) (PubMed).

Samarpita, Doss, Ganesan, Rasool: "Interleukin 17 under hypoxia mimetic condition augments osteoclast mediated bone erosion and expression of HIF-1α and MMP-9." in: Cellular immunology, Vol. 332, pp. 39-50, (2018) (PubMed).

Yao, Zhao, Tang, Liang, Liu, Dong, Zou, Cai: "The receptor for advanced glycation end products is required for β-catenin stabilization in a chemical-induced asthma model." in: British journal of pharmacology, Vol. 173, Issue 17, pp. 2600-13, (2017) (PubMed).

Details zu MMP 9

Target: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Andere Bezeichnung: MMP9 (MMP9 Produkte)

Synonyme: CLG4B antikoerper, GELB antikoerper, MANDP2 antikoerper, MMP-9 antikoerper, AW743869 antikoerper, B/MMP9 antikoerper, Clg4b antikoerper, pro-MMP-9 antikoerper, mmp-9 antikoerper, fgMMP-9 antikoerper, mmp9 antikoerper, ZFMMP-9 antikoerper, wu:fb02g06 antikoerper, wu:fb07b05 antikoerper, wu:fi98c09 antikoerper, wu:fj05a08 antikoerper, zgc:64165 antikoerper, clg4b antikoerper, gelb antikoerper, mandp2 antikoerper, matrix metallopeptidase 9 antikoerper, collagenase antikoerper, matrix metalloproteinase 9 antikoerper, matrix metallopeptidase 9 S homeolog antikoerper, MMP9 antikoerper, RB3913 antikoerper, BPSS0666 antikoerper, Sbal_3732 antikoerper, Bcer98_0486 antikoerper, Shew185_0630 antikoerper, Shal_3056 antikoerper, Sbal195_0657 antikoerper, Lbys_3550 antikoerper, Palpr_2084 antikoerper, Mmp9 antikoerper, mmp9 antikoerper, mmp9.S antikoerper

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.,MMP9,CLG4B,GELB,MANDP2,MMP-9,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,MMP9

Molekulargewicht: 78 kDa

Gen-ID: 4318

UniProt: P14780

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events