MMP 9 Antikörper (C-Term)

Produktnummer ABIN390154

Produktdetails anti-MMP 9 Antikörper

Target: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Bindungsspezifität: AA 644-673, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP 9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MMP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 644-673 amino acids from the C-terminal region of human MMP9.

Klon: RB02019-RB02020

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. IHC-P: 1:50~100. IHC-P: 1:50~100. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-MMP 9 Antikörper (ABIN390154)

Dou, Cao, Wang, Zhang, Huang, Lian, Xie, Wang: "EFEMP1 inhibits migration of hepatocellular carcinoma by regulating MMP2 and MMP9 via ERK1/2 activity." in: Oncology reports, Vol. 35, Issue 6, pp. 3489-95, (2017) (PubMed).

Du, Wang, Tan, Li, Huang, Huang, Yang, Zhang, Wang, Huang, Huang: "Nkx2-5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E-Deficient Mice." in: Journal of the American Heart Association, Vol. 5, Issue 12, (2017) (PubMed).

Huang, Chiu, Chou, Su, Chen, Chai, Huang, Huang, Yuan, Lee: "Association of MMP-2 and MMP-9 expression with recurrences in primary spontaneous pneumothorax." in: The Kaohsiung journal of medical sciences, Vol. 33, Issue 1, pp. 17-23, (2017) (PubMed).

Dai, Duan, Duan, Zhou, He, Tu, Shen: "Down-regulation of TCF21 by hypermethylation induces cell proliferation, migration and invasion in colorectal cancer." in: Biochemical and biophysical research communications, (2015) (PubMed).

Alfonso-Loeches, Ureña-Peralta, Morillo-Bargues, Gómez-Pinedo, Guerri: "Ethanol-Induced TLR4/NLRP3 Neuroinflammatory Response in Microglial Cells Promotes Leukocyte Infiltration Across the BBB." in: Neurochemical research, (2015) (PubMed).

Shi, Shang, Pan, Wang, Jiang, Hao, Zhang, Cai, Xu, Zhan, Wang: "Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 23, pp. 6153-62, (2014) (PubMed).

Shi, Yang, Shen, Yang, Xu, Qiu, Sun, Zhang, Wang, Zhu, Qin, Tang, Fan, Zhou: "High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery." in: Cancer, Vol. 119, Issue 5, pp. 993-1003, (2013) (PubMed).

Wu, Wang, Guo, Ye, Wang, Yuan, Yao, Shang: "A lipoxin A4 analog ameliorates blood-brain barrier dysfunction and reduces MMP-9 expression in a rat model of focal cerebral ischemia-reperfusion injury." in: Journal of molecular neuroscience : MN, Vol. 46, Issue 3, pp. 483-91, (2012) (PubMed).

Chen, Wang, Hu, Chang, Liao, Dai, Juo: "OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 5, pp. 1718-28, (2011) (PubMed).

Details zu MMP 9

Target: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Andere Bezeichnung: MMP9 (MMP9 Produkte)

Synonyme: CLG4B antikoerper, GELB antikoerper, MANDP2 antikoerper, MMP-9 antikoerper, AW743869 antikoerper, B/MMP9 antikoerper, Clg4b antikoerper, pro-MMP-9 antikoerper, mmp-9 antikoerper, fgMMP-9 antikoerper, mmp9 antikoerper, ZFMMP-9 antikoerper, wu:fb02g06 antikoerper, wu:fb07b05 antikoerper, wu:fi98c09 antikoerper, wu:fj05a08 antikoerper, zgc:64165 antikoerper, clg4b antikoerper, gelb antikoerper, mandp2 antikoerper, matrix metallopeptidase 9 antikoerper, collagenase antikoerper, matrix metalloproteinase 9 antikoerper, matrix metallopeptidase 9 S homeolog antikoerper, MMP9 antikoerper, RB3913 antikoerper, BPSS0666 antikoerper, Sbal_3732 antikoerper, Bcer98_0486 antikoerper, Shew185_0630 antikoerper, Shal_3056 antikoerper, Sbal195_0657 antikoerper, Lbys_3550 antikoerper, Palpr_2084 antikoerper, Mmp9 antikoerper, mmp9 antikoerper, mmp9.S antikoerper

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Molekulargewicht: 78458

Gen-ID: 4318

NCBI Accession: NP_004985

UniProt: P14780

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events