UBE2D1 Antikörper (AA 1-147)

Produktnummer ABIN3015752

Produktdetails anti-UBE2D1 Antikörper

Target: UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

Bindungsspezifität: AA 1-147

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MALKRIQKEL SDLQRDPPAH CSAGPVGDDL FHWQATIMGP PDSAYQGGVF FLTVHFPTDY PFKPPKIAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV PDIAQIYKSD KEKYNRHARE WTQKYAM

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human UBE2D1 (NP_003329.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu UBE2D1

Target: UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

Andere Bezeichnung: UBE2D1 (UBE2D1 Produkte)

Synonyme: E2(17)KB1 antikoerper, SFT antikoerper, UBC4/5 antikoerper, UBCH5 antikoerper, UBCH5A antikoerper, ube2d1 antikoerper, wu:fc16h06 antikoerper, zgc:73096 antikoerper, e2(17)kb1 antikoerper, sft antikoerper, ubc4/5 antikoerper, ubch5 antikoerper, ubch5a antikoerper, ubiquitin conjugating enzyme E2 D1 antikoerper, ubiquitin-conjugating enzyme E2D 1 antikoerper, ubiquitin-conjugating enzyme E2D 1b antikoerper, ubiquitin conjugating enzyme E2 D1 S homeolog antikoerper, UBE2D1 antikoerper, Ube2d1 antikoerper, ube2d1b antikoerper, ube2d1.S antikoerper, ube2d1 antikoerper

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.,UBE2D1,E2(17)KB1,SFT,UBC4/5,UBCH5,UBCH5A,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,UBE2D1

Molekulargewicht: 16 kDa

Gen-ID: 7321

UniProt: P51668

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades