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PLVAP Antikörper (Biotin)

PLVAP Reaktivität: Maus FACS, IHC, IHC (fro) Wirt: Ratte Monoclonal MECA-32 Biotin
Produktnummer ABIN298900
  • Target Alle PLVAP Antikörper anzeigen
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    Reaktivität
    • 28
    • 6
    • 1
    Maus
    Wirt
    • 21
    • 7
    • 4
    Ratte
    Klonalität
    • 22
    • 9
    Monoklonal
    Konjugat
    • 19
    • 5
    • 2
    • 2
    • 2
    • 2
    Dieser PLVAP Antikörper ist konjugiert mit Biotin
    Applikation
    • 30
    • 21
    • 16
    • 8
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    Recognizes murine plasmalemma vesicle-associated protein (PLVAP), a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae. In adult and embryonic mice, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, cardiac and brain tissues. In embryonic mice, PLVAP expression, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated. In humans, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, including glioblastoma and metastatic carcinoma, as well as other cerebral disorders associated with blood-brain barrier disruption, such as acute ischemia. PLVAP represents a novel marker of brain tumor angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target.
    Aufreinigung
    Affinity purified
    Immunogen


    Type of Immunogen: Native protein
    Klon
    MECA-32
    Isotyp
    IgG2a
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    Discover our top product PLVAP Primärantikörper
  • Applikationshinweise
    Approved: Flo, IHC, IHC-Fr (1:1 - 1:10)

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.
    Kommentare

    Target Species of Antibody: Mouse

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Short term: -20°C
    Long term: -20°C.
  • Target
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    Andere Bezeichnung
    PV1 / PLVAP (PLVAP Produkte)
    Synonyme
    MECA32 antikoerper, Pv1 antikoerper, FELS antikoerper, PV-1 antikoerper, PV1 antikoerper, gp68 antikoerper, plasmalemma vesicle associated protein antikoerper, Plvap antikoerper, PLVAP antikoerper
    Hintergrund
    Name/Gene ID: PLVAP

    Synonyms: PLVAP, gp68, FELS, Plasmalemma vesicle protein 1, PV-1, PV1
    Gen-ID
    83483
    UniProt
    Q9BX97
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