JNK2 Antikörper (AA 373-389)

Produktnummer ABIN293095

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch JNK2 in WB, IHC und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Schwein, Kaninchen, Rind (Kuh) und Fledermaus.

Kurzübersicht für JNK2 Antikörper (AA 373-389) (ABIN293095)

Target: JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))

Reaktivität: Human, Schwein, Kaninchen, Rind (Kuh), Fledermaus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JNK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-JNK2 Antikörper

Bindungsspezifität: AA 373-389

Spezifität: A synthetic peptide corresponding to amino acids 373-389 (KDQPSDAAVSSNATPSQ) of human JNK2 was used as immunogen. This amino acid sequence is 100 % homologous in cow and dog, and 94 % in mouse and rat.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Elephant, Bat, Bovine, Rabbit, Pig (100%) Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Horse (94%) Platypus (82%).

Aufreinigung: Protein G purified

Immunogen: A synthetic peptide corresponding to amino acids 373-389 (KDQPSDAAVSSNATPSQ) of human JNK2, GenBank no. gi|21237736|ref|NP_002743.3|. This amino sequence is 100% homologous in cow and dog, and 94% in mouse and rat. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Elephant, Bat, Bovine, Rabbit, Pig (100%), Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Horse (94%), Platypus (82%).

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (10 μg/mL), WB (1 - 3 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Details zu JNK2

Target: JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))

Andere Bezeichnung: MAPK9 / JNK2 / SAPK

Hintergrund: Name/Gene ID: MAPK9
Subfamily: MAPK
Family: Protein Kinase

Synonyms: MAPK9, C-Jun kinase 2, C-Jun N-terminal kinase 2, JNK2B, JNK2, JNK2ALPHA, MAP kinase 9, p54a, JNK2BETA, PRKM9, SAPK, MAPK 9, p54aSAPK, SAPK1a, JNK-55, JNK2A, Jun kinase

Gen-ID: 5601

NCBI Accession: NP_002743

UniProt: P45984

Pathways: MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, S100 Proteine