JNK2 Antikörper (AA 227-382)

Produktnummer ABIN7193450

Produktdetails anti-JNK2 Antikörper

Target: JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))

Bindungsspezifität: AA 227-382

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser JNK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human MAPK9 (AA: 227-382) expressed in E. coli.

Klon: 2F6H11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu JNK2

Target: JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))

Andere Bezeichnung: MAPK9 (MAPK9 Produkte)

Synonyme: MAPK9 antikoerper, JNK-55 antikoerper, JNK2 antikoerper, JNK2A antikoerper, JNK2ALPHA antikoerper, JNK2B antikoerper, JNK2BETA antikoerper, PRKM9 antikoerper, SAPK antikoerper, SAPK1a antikoerper, p54a antikoerper, p54aSAPK antikoerper, AI851083 antikoerper, Prkm9 antikoerper, JNK2-ALPHA1 antikoerper, MAP kinase 9 antikoerper, mitogen-activated protein kinase 9 antikoerper, MAP kinase 9 antikoerper, MAPK9 antikoerper, Mapk9 antikoerper, MPK9 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

Aliases: JNK2, SAPK, p54a, JNK2A, JNK2B, PRKM9, JNK-55, SAPK1a, JNK2BETA, p54aSAPK, JNK2ALPHA

Molekulargewicht: 48.1 kDa

Gen-ID: 5601

Pathways: MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, S100 Proteine