ATR Antikörper (Internal Region)

Produktnummer ABIN292420

Produktdetails anti-ATR Antikörper

Target: ATR (ATR serine/threonine kinase (ATR))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund, Fisch, Affe, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATR Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Spezifität: A BLAST analysis was used to suggest cross- reactivity with ATR from human, mouse, rat, monkey, dog, fish and Xenopus sources based on a 100 % homology with the immunizing sequence. Cross-reactivity with ATR from other sources has not been determined

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to an internal region of human ATR protein.

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (1:15000 - 1:70000), WB (1:1000 - 1:5000)

Usage: This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 301 kD in size corresponding to ATR by western blotting in the appropriate cell lysate or extract. Lysates from HeLa, U2OS, RAW264.7 or HEK293 cells are suggested for western blotting. ATR is ubiquitously expressed, with highest expression levels in the testes. Note that isoform 2 is found in pancreas, placenta and liver but not in heart, testis and ovary.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride,  pH 7.2, 0.01 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu ATR

Target: ATR (ATR serine/threonine kinase (ATR))

Andere Bezeichnung: ATR (ATR Produkte)

Synonyme: FCTCS antikoerper, FRP1 antikoerper, MEC1 antikoerper, SCKL antikoerper, SCKL1 antikoerper, ATR serine/threonine kinase antikoerper, ataxia telangiectasia and Rad3 related antikoerper, ATR antikoerper, Atr antikoerper

Hintergrund: Name/Gene ID: ATR
Subfamily: PI3/PI4
Family: Protein Kinase

Synonyms: ATR, FRAP-related protein-1, FCTCS, SCKL1, MEC1, Protein kinase ATR, Rad3 related protein, SCKL, FRAP-related protein 1, FRP1

Gen-ID: 545

UniProt: Q13535

Pathways: Positive Regulation of Response to DNA Damage Stimulus