TRPA1 Antikörper

Produktnummer ABIN290051

Produktdetails anti-TRPA1 Antikörper

Target: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Aufreinigung: This antibody was established from the serum of a rabbit immunized with the partial peptide corresponding to amino acid 12-24 of mouse TRPA1, and purified by peptideaffinity chromatography.

Immunogen: Partial peptide of Mouse TRPA1

Anwendungsinformationen

Applikationshinweise: Working dilution For Western blotting 1.6 ug/ml. For Immunoprecipitation 1.6 ug/ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu TRPA1

Target: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Andere Bezeichnung: TRPA1 (TRPA1 Produkte)

Synonyme: trpa1 antikoerper, ANKTM1 antikoerper, Anktm1 antikoerper, CG5751 antikoerper, CG5761 antikoerper, CT18073 antikoerper, DmTRPA1 antikoerper, Dmel\\CG5751 antikoerper, TRPA antikoerper, TRPA1 antikoerper, TrpA antikoerper, dANKTM1 antikoerper, dTRPA antikoerper, dTRPA1 antikoerper, dTrpA antikoerper, dTrpA1 antikoerper, dtrpA1 antikoerper, trpA1 antikoerper, GLEAN_02449 antikoerper, FEPS antikoerper, transient receptor potential cation channel, subfamily A, member 1a antikoerper, Transient receptor potential cation channel A1 antikoerper, transient receptor potential cation channel subfamily A member 1 antikoerper, transient receptor potential A1 antikoerper, tryptophan synthase subunit alpha 1 antikoerper, transient receptor potential cation channel, subfamily A, member 1 antikoerper, TRPA cation channel homolog antikoerper, trpa1a antikoerper, TrpA1 antikoerper, TRPA1 antikoerper, LOC658860 antikoerper, LOC694623 antikoerper, trpA1 antikoerper, trpa1 antikoerper, Trpa1 antikoerper, trpa-1 antikoerper

Hintergrund: Mammals feel a wide range of temperature spanning from cold to heat with specialized neurons in theperipheral nervous system. With this range, temperatures over about 43 degrees C and below about 15 degrees Cevoke not only a thermal sensation, but also a feeling of pain.Nine thermosensitive ion channels have been reported, all of which belong to TRP (transient receptorpotential) superfamily. They are expressed in sensory tissues, such as nociceptors and skin. Among them, TRPA1(TRP cation channel, subfamily A, member 1) has been identified as cold-sensitive ion channel. TRPA1 isactivated at approximately 17 degrees C, a temperature that is reported as painfully cold by humans.In addition to noxious cold, TRPA1 is activated pungent ingredients present in mustard, garlic, ginger, clove,wintergreen and cinnamon all and found in a subset of nociceptive sensory neurons where it is coexpressed withTRPV1/VR1 (capsaicin/heat receptor). Moreover, TRPA1 has been proposed to be a component of themechanosensitive transduction channel of vertebrate hair cells.This antibody will be very useful to research the nocifensive (thermosensitive and mechanosensitive) responseto pain.