TRPA1 Antikörper (Middle Region)

Produktnummer ABIN2776190

Produktdetails anti-TRPA1 Antikörper

Target: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Pferd, Rind (Kuh), Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: KCTDRLDEDG NTALHFAARE GHAKAVALLL SHNADIVLNK QQASFLHLAL

Homologie: Cow: 93%, Dog: 90%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TRPA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRPA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1119 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TRPA1 Antikörper (ABIN2776190)

Trevisan, Benemei, Materazzi, De Logu, De Siena, Fusi, Fortes Rossato, Coppi, Marone, Ferreira, Geppetti, Nassini: "TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress." in: Brain : a journal of neurology, Vol. 139, Issue Pt 5, pp. 1361-77, (2016) (PubMed).

Kun, Perkecz, Knie, Sétáló, Tornóczki, Pintér, Bán: "TRPA1 receptor is upregulated in human oral lichen planus." in: Oral diseases, Vol. 23, Issue 2, pp. 189-198, (2016) (PubMed).

Pierce, Ryals, Wang, Christianson: "Vaginal hypersensitivity and hypothalamic-pituitary-adrenal axis dysfunction as a result of neonatal maternal separation in female mice." in: Neuroscience, Vol. 263, pp. 216-30, (2014) (PubMed).

Nassini, Pedretti, Moretto, Fusi, Carnini, Facchinetti, Viscomi, Pisano, Stokesberry, Brunmark, Svitacheva, McGarvey, Patacchini, Damholt, Geppetti, Materazzi: "Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation." in: PLoS ONE, Vol. 7, Issue 8, pp. e42454, (2012) (PubMed).

Details zu TRPA1

Target: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Andere Bezeichnung: TRPA1 (TRPA1 Produkte)

Synonyme: trpa1 antikoerper, ANKTM1 antikoerper, Anktm1 antikoerper, CG5751 antikoerper, CG5761 antikoerper, CT18073 antikoerper, DmTRPA1 antikoerper, Dmel\\CG5751 antikoerper, TRPA antikoerper, TRPA1 antikoerper, TrpA antikoerper, dANKTM1 antikoerper, dTRPA antikoerper, dTRPA1 antikoerper, dTrpA antikoerper, dTrpA1 antikoerper, dtrpA1 antikoerper, trpA1 antikoerper, GLEAN_02449 antikoerper, FEPS antikoerper, transient receptor potential cation channel, subfamily A, member 1a antikoerper, Transient receptor potential cation channel A1 antikoerper, transient receptor potential cation channel subfamily A member 1 antikoerper, transient receptor potential A1 antikoerper, tryptophan synthase subunit alpha 1 antikoerper, transient receptor potential cation channel, subfamily A, member 1 antikoerper, TRPA cation channel homolog antikoerper, trpa1a antikoerper, TrpA1 antikoerper, TRPA1 antikoerper, LOC658860 antikoerper, LOC694623 antikoerper, trpA1 antikoerper, trpa1 antikoerper, Trpa1 antikoerper, trpa-1 antikoerper

Hintergrund: The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined, however, studies indicate the function may involve a role in sig
Alias Symbols: ANKTM1
Protein Interaction Partner: UBC, CYLD,
Protein Size: 1119

Molekulargewicht: 127 kDa

Gen-ID: 8989

NCBI Accession: NM_007332, NP_015628

UniProt: O75762