Adiponectin Receptor 1 Antikörper

Produktnummer ABIN290045

Produktdetails anti-Adiponectin Receptor 1 Antikörper

Target: Adiponectin Receptor 1 (ADIPOR1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adiponectin Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody was prepared from the serum of a rabbit immunized with a partial peptide representing the N-terminal domain of Human AdipoR1, and purified bypeptide affinity chromatography.

Immunogen: Partial peptide of Human AdipoR1

Anwendungsinformationen

Applikationshinweise: Working dilution For Western blotting: 1.0ug/ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu Adiponectin Receptor 1

Target: Adiponectin Receptor 1 (ADIPOR1)

Andere Bezeichnung: AdipoR1 (ADIPOR1 Produkte)

Synonyme: ADIPOR1 antikoerper, adipor1 antikoerper, zgc:92893 antikoerper, ACDCR1 antikoerper, CGI45 antikoerper, PAQR1 antikoerper, TESBP1A antikoerper, 2810031L11Rik antikoerper, CGI-45 antikoerper, Paqr1 antikoerper, zgc:55386 antikoerper, wu:fj02d08 antikoerper, acdcr1 antikoerper, cgi-45 antikoerper, cgi45 antikoerper, paqr1 antikoerper, tesbp1a antikoerper, MGC53458 antikoerper, Adipor1 antikoerper, adiponectin receptor 1 antikoerper, adiponectin receptor 1a antikoerper, adiponectin receptor 1b antikoerper, adiponectin receptor 1 S homeolog antikoerper, adiponectin receptor 1 L homeolog antikoerper, ADIPOR1 antikoerper, adipor1a antikoerper, Adipor1 antikoerper, adipor1b antikoerper, adipor1 antikoerper, adipor1.S antikoerper, adipor1.L antikoerper

Hintergrund: Obesity is a common etiology of diabetes mellitus and other diseases. Certain adipocytokines areconsidered beneficial due to their ability to enhance insulin sensitivity, while others, considereddetrimental, enhance insulin resistance.The beneficial adipocytokine adiponectin displays both anti-diabetic and anti-arteriosclerotic effects. Two distinct adiponectin receptors have been identified. Both AdipoR1 and AdipoR2 are seven-passtransmembrane receptors but are structurally, topologically, and functionally distinct from G-proteincoupled receptors (GPCR) (Ref.1). AdipoR1 is most abundant in muscle whereas AdipoR2 is mostabundant in liver. Both receptors promote fatty acid oxidation and glucose uptake by AMP-activatedprotein kinase and PPAR gamma.PPAR agonists are reported to increase expression of activated adiponectin. PPAR gamma agonists also increase expression of adiponectin receptors (Ref.2). Such findings have focused attention on the role of AdipoR1 in PPAR agonist development.

Pathways: AMPK Signaling