AJUBA Antikörper

Produktnummer ABIN290002

Produktdetails anti-AJUBA Antikörper

Target: AJUBA (Ajuba LIM Protein (AJUBA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AJUBA Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunocytochemistry (ICC)

Aufreinigung: This antibody was purified from rabbit serum by affinity chromatography.

Immunogen: GST-Human Ajuba fusion Protein

Anwendungsinformationen

Applikationshinweise: Working dilution For Immunoprecipitation , 10 ug/mlFor Immnocytochemistry , 2-5 ug/ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu AJUBA

Target: AJUBA (Ajuba LIM Protein (AJUBA))

Andere Bezeichnung: Ajuba (AJUBA Produkte)

Synonyme: JUB antikoerper, Jub antikoerper, ajuba LIM protein antikoerper, AJUBA antikoerper, Ajuba antikoerper

Hintergrund: Aurora-A(Aurora-A/STK-15/Aik) encoding a centrosome-associated Ser/Thr kinase, is amplified andoverexpressed in many cancer cell types, and is involved in the induction of centrosomeduplication-distribution abnormalities and aneuploidy in mammalian cells. In vitro transformation activityof Aurora-A suggested to be a potential oncogene. Recent research elucidated that Ajuba, Aurora-A bindingprotein, induces the autophosphorylation and consequent activation of Aurora-A . In the future thisantibody will contribute the research progress whether Ajuba and Aurora-A are involed in tumorigenesis.This antibody is useful for immunoprecipitation and immunocytochemistry.

Pathways: Chromatin Binding, Cell-Cell Junction Organization