SLC22A6 Antikörper

Produktnummer ABIN289973

Produktdetails anti-SLC22A6 Antikörper

Target: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC22A6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT1 by peptide affinity chromatography.

Immunogen: Partial peptide of Human Organic Anion Transporter 1(OAT1)

Anwendungsinformationen

Applikationshinweise: Working dilution for immunohistochemistry 5ug/ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu SLC22A6

Target: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Andere Bezeichnung: Organic Anion Transporter 1(OAT1) (SLC22A6 Produkte)

Synonyme: HOAT1 antikoerper, OAT1 antikoerper, PAHT antikoerper, ROAT1 antikoerper, NKT antikoerper, Oat1 antikoerper, Orctl1 antikoerper, mOat1 antikoerper, slc22a6 antikoerper, zgc:77073 antikoerper, SLC22A6 antikoerper, Paht antikoerper, Roat1 antikoerper, nkt antikoerper, oat1 antikoerper, oat1-B antikoerper, paht antikoerper, roat1 antikoerper, slc22a6-B antikoerper, Slc22a6 antikoerper, solute carrier family 22 member 6 antikoerper, solute carrier family 22 (organic anion transporter), member 6 antikoerper, solute carrier family 22 (organic anion transporter), member 6, like antikoerper, Solute carrier family 22 member 6 antikoerper, solute carrier family 22 (organic anion transporter), member 6 S homeolog antikoerper, SLC22A6 antikoerper, Slc22a6 antikoerper, slc22a6l antikoerper, s22a6 antikoerper, slc22a6.S antikoerper

Hintergrund: To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for theelimination, hepatic one through bile and renal one to urine. The transporter fall into various transportsystems by the transportative substrate. In particular, oraganic ion transporter family is comprised oforganic anion transport family (OAT), oraganic cation transport family (OCT), OCTN/carnitine transportfamily, and OAT are multispecific organic anion transpoters, the substrates of which include a lot of bothendogeneous and exogeneous anions .Human Organic anion transporter 1(OAT1) encodes a 563 amino acid residue protein, and which ispredicted 12 putative membrane-spanning protein. Human OAT1 was found to be expressed predominantlyin the kidney and only weakly in the brain. OAT1 mediates the Na+-independent transport of organic anions,such as PAH (p-aminohippurate), cyclic nucleotides, prostanoides, dicaroxylates, and many anion drugs.This antibody has been proved to be useful for immunohistochemistry .

Pathways: Dicarboxylic Acid Transport