SLC7A5 Antikörper

Produktnummer ABIN289962

Produktdetails anti-SLC7A5 Antikörper

Target: SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC7A5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: This antidody was purified from rabbit serum immunized with synthesized peptide ofC- end of human LAT1 and has been proved to be useful for the immunohistochemistry

Immunogen: Partial peptide of Human L-type Amino Acid Transporter 1(LAT1)

Anwendungsinformationen

Applikationshinweise: Working dilution for immunohistochemistry: 5-10ug/ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu SLC7A5

Target: SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))

Andere Bezeichnung: L-type Amino Acid Transporter 1(LAT1) (SLC7A5 Produkte)

Synonyme: 4F2LC antikoerper, CD98 antikoerper, D16S469E antikoerper, E16 antikoerper, LAT1 antikoerper, MPE16 antikoerper, hLAT1 antikoerper, D0H16S474E antikoerper, TA1 antikoerper, JHI-21 antikoerper, SLC7A5 antikoerper, LAT-1 antikoerper, slc7a5a antikoerper, 4F2 antikoerper, 4F2HC antikoerper, AI314110 antikoerper, Cd98 antikoerper, Ly-10 antikoerper, Ly-m10 antikoerper, Ly10 antikoerper, Mdu1 antikoerper, Mgp-2hc antikoerper, NACAE antikoerper, solute carrier family 7 member 5 antikoerper, solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 antikoerper, solute carrier family 7 (amino acid transporter light chain, L system), member 5 antikoerper, solute carrier family 7 member 5 S homeolog antikoerper, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antikoerper, SLC7A5 antikoerper, Slc7a5 antikoerper, slc7a5.S antikoerper, Slc3a2 antikoerper

Hintergrund: Mammalian amino acid transport system is consisted of large variety of transporters, with the reflection ofamino acid molecule variety, and is classfied into various transport systems by the transportative substrateselectivity and the Na+ dependence with the reflection of amino acid molecule variety.L-type amino acid transporter 1 (LAT1) is a predicted 12 membrane-spanning protein and is uniquebecause it requires an additional single membrane spanning protein, 4F2 heavy chain (4F2hc:CD98), for itsfunctional expression. L-type is Na+ -independent neutral amino acid transporter agency and essential forthe transporter of large neutral amino acid such as Leucine, Isoleucine, Varine through the plasmamembrane. LAT1 is, thus transporter responsible for the permeation of aromatic or branched-chain aminoacids and amino acid-related drugs such as L-DOPA. LAT has been proposed to be one of the majornutrient transport systems at the blood-brain barrier. Highly regulated nature and high level of expression intumor cell lines, LAT is thought to be up-regulated to support the high protein synthesis for cell glowth andcell activation.This antibody has been proved to be useful for the immunohistochemistry.