SLC7A5 Antikörper (C-Term)

Produktnummer ABIN6265149

Produktdetails anti-SLC7A5 Antikörper

Target: SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC7A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: SLC7A5 Antibody detects endogenous levels of total SLC7A5.

Homologie: Pig,Zebrafish,Bovine,Sheep,Rabbit,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SLC7A5, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SLC7A5

Target: SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))

Andere Bezeichnung: SLC7A5 (SLC7A5 Produkte)

Synonyme: 4F2LC antikoerper, CD98 antikoerper, D16S469E antikoerper, E16 antikoerper, LAT1 antikoerper, MPE16 antikoerper, hLAT1 antikoerper, D0H16S474E antikoerper, TA1 antikoerper, JHI-21 antikoerper, SLC7A5 antikoerper, LAT-1 antikoerper, slc7a5a antikoerper, 4F2 antikoerper, 4F2HC antikoerper, AI314110 antikoerper, Cd98 antikoerper, Ly-10 antikoerper, Ly-m10 antikoerper, Ly10 antikoerper, Mdu1 antikoerper, Mgp-2hc antikoerper, NACAE antikoerper, solute carrier family 7 member 5 antikoerper, solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 antikoerper, solute carrier family 7 (amino acid transporter light chain, L system), member 5 antikoerper, solute carrier family 7 member 5 S homeolog antikoerper, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antikoerper, SLC7A5 antikoerper, Slc7a5 antikoerper, slc7a5.S antikoerper, Slc3a2 antikoerper

Hintergrund:

Description: Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts. When associated with LAPTM4B, recruits SLC3A2 and SLC7A5 to lysosomes to promote leucine uptake into these organelles and is required for mTORC1 activation (PubMed:25998567).

Gene: SLC7A5

Molekulargewicht: 55 kDa

Gen-ID: 8140

UniProt: Q01650