SERPING1 Antikörper (Center)

Produktnummer ABIN2856082

Produktdetails anti-SERPING1 Antikörper

Target: SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))

Bindungsspezifität: Center

Reaktivität: Human, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPING1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktmerkmale: Rabbit Polyclonal antibody to C1 inhibitor (serpin peptidase inhibitor, clade G (C1 inhibitor), member 1)
C1 inhibitor antibody [N1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human C1 inhibitor. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Immunohistochemistry Assay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunohistochemistryAssay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-SERPING1 Antikörper (ABIN2856082)

Kwon, Kim, Hwang, Kim, Kim, Kim, Lee, Im, Lee, Hwang: "Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genes." in: Transgenic research, Vol. 26, Issue 1, pp. 153-163, (2018) (PubMed).

Hayashi, Ushizawa, Hosoe, Takahashi: "Differential gene expression of serine protease inhibitors in bovine ovarian follicle: possible involvement in follicular growth and atresia." in: Reproductive biology and endocrinology : RB&E, Vol. 9, pp. 72, (2011) (PubMed).

Details zu SERPING1

Target: SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))

Andere Bezeichnung: C1 Inhibitor (SERPING1 Produkte)

Synonyme: fb64f02 antikoerper, im:7159527 antikoerper, si:dkeyp-110g5.2 antikoerper, wu:fb60c09 antikoerper, wu:fb62a08 antikoerper, wu:fb64f02 antikoerper, LOC100136072 antikoerper, C1-INH antikoerper, C1INH antikoerper, C1nh antikoerper, C1IN antikoerper, C1NH antikoerper, HAE1 antikoerper, HAE2 antikoerper, serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 antikoerper, C1 inhibitor antikoerper, serpin family G member 1 antikoerper, serine (or cysteine) peptidase inhibitor, clade G, member 1 antikoerper, serping1 antikoerper, LOC100136072 antikoerper, SERPING1 antikoerper, Serping1 antikoerper

Hintergrund: This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

Cellular Localization: Secreted

Molekulargewicht: 55 kDa

Gen-ID: 710

Pathways: Komplementsystem