SCN3B Antikörper (Center)

Produktnummer ABIN2855827

Produktdetails anti-SCN3B Antikörper

Target: SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Affe, Ratte (Rattus), Rind (Kuh)

Kreuzreaktivität (Details): Mouse (98 %), Monkey (99 %), Rat (98 %), Bovine (98 %)

Produktmerkmale: Rabbit polyclonal antibody to SCN3B (sodium channel, voltage-gated, type III, beta)
SCN3B antibody [N1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SCN3B. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.55 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-SCN3B Antikörper (ABIN2855827)

Zhao, Sun, Zeng, Li, Zhou, Zhou, Xue, Cheng, Xia, Wang, Tu: "Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells." in: BMC cardiovascular disorders, Vol. 16, pp. 1, (2016) (PubMed).

Details zu SCN3B

Target: SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))

Andere Bezeichnung: SCN3B (SCN3B Produkte)

Synonyme: 1110001K16Rik antikoerper, 4833414B02Rik antikoerper, Scnb3 antikoerper, HSA243396 antikoerper, SCNB3 antikoerper, sodium voltage-gated channel beta subunit 3 antikoerper, sodium channel, voltage-gated, type III, beta antikoerper, SCN3B antikoerper, Scn3b antikoerper

Hintergrund: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molekulargewicht: 25 kDa

Gen-ID: 55800