CD13 Antikörper
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- Target Alle CD13 (ANPEP) Antikörper anzeigen
- CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD13 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human
- Produktmerkmale
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Rabbit Polyclonal antibody to CD13 (alanyl (membrane) aminopeptidase)
CD13 antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human CD13. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product ANPEP Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: THP-1 , HL-60 , ANPEP-transfected 293T
Validation: Overexpression
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.82 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
- Andere Bezeichnung
- alanyl aminopeptidase, membrane (ANPEP Produkte)
- Synonyme
- APN antikoerper, CD13 antikoerper, GP150 antikoerper, LAP1 antikoerper, P150 antikoerper, PEPN antikoerper, A2AP antikoerper, AAP antikoerper, ALPHA-2-PI antikoerper, API antikoerper, PLI antikoerper, AAT1 antikoerper, ALT1 antikoerper, GPT1 antikoerper, Gpt1 antikoerper, Apn antikoerper, pepN antikoerper, SC8E4A.13 antikoerper, 1300007J06Rik antikoerper, 2310022B03Rik antikoerper, ALT antikoerper, Gpt-1 antikoerper, AP-M antikoerper, AP-N antikoerper, Cd13 antikoerper, Apm antikoerper, KZP antikoerper, Lap1 antikoerper, rAPN antikoerper, APDE antikoerper, p150 antikoerper, anpep antikoerper, fb64c05 antikoerper, wu:fb64c05 antikoerper, zgc:136771 antikoerper, alanyl aminopeptidase, membrane antikoerper, serpin family F member 2 antikoerper, glutamic--pyruvic transaminase antikoerper, aminopeptidase N antikoerper, aminopeptidase antikoerper, aminopeptidase n antikoerper, glutamic pyruvic transaminase, soluble antikoerper, alanyl (membrane) aminopeptidase antikoerper, membrane alanyl aminopeptidase antikoerper, alanyl (membrane) aminopeptidase b antikoerper, alanyl aminopeptidase, membrane L homeolog antikoerper, ANPEP antikoerper, SERPINF2 antikoerper, GPT antikoerper, Gpt antikoerper, Apn2 antikoerper, Apn1 antikoerper, SCO2643 antikoerper, pepN antikoerper, Shewana3_0897 antikoerper, Alvin_1024 antikoerper, Ndas_3413 antikoerper, Saut_1544 antikoerper, Fbal_1877 antikoerper, ML5_3424 antikoerper, Despr_1988 antikoerper, Mesop_5365 antikoerper, Anpep antikoerper, LOC101744250 antikoerper, anpepb antikoerper, anpep.L antikoerper
- Hintergrund
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Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
Cellular Localization: Cell membrane, Single-pass type II membrane protein , Cytoplasm , cytosol , Cell membrane , Cytoplasm , cytosol - Molekulargewicht
- 110 kDa
- Gen-ID
- 290
- UniProt
- P15144
- Pathways
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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