Endoglin Antikörper
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- Target Alle Endoglin (ENG) Antikörper anzeigen
- Endoglin (ENG)
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Endoglin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
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Rabbit Polyclonal antibody to CD105 (endoglin)
CD105 antibody [N3C3] - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human CD105. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product ENG Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: HUVEC
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Endoglin (ENG)
- Andere Bezeichnung
- endoglin (ENG Produkte)
- Synonyme
- ENG antikoerper, MGC137842 antikoerper, DKFZp469D0419 antikoerper, END antikoerper, HHT1 antikoerper, ORW1 antikoerper, AI528660 antikoerper, AI662476 antikoerper, CD105 antikoerper, S-endoglin antikoerper, endoglin antikoerper, ENG antikoerper, Eng antikoerper
- Hintergrund
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This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Membrane, Single-pass type I membrane protein - Molekulargewicht
- 71 kDa
- Gen-ID
- 2022
- UniProt
- P17813
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