CCR8 Antikörper (Center)

Produktnummer ABIN2854721

Produktdetails anti-CCR8 Antikörper

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Rind (Kuh)

Kreuzreaktivität (Details): Bovine (91 %)

Produktmerkmale: Rabbit Polyclonal antibody to CCR8 (chemokine (C-C motif) receptor 8)
CCR8 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human CCR8. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: HeLa

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Andere Bezeichnung: CCR8 (CCR8 Produkte)

Synonyme: CC-CKR-8 antikoerper, CCR-8 antikoerper, CDw198 antikoerper, CKRL1 antikoerper, CMKBR8 antikoerper, CMKBRL2 antikoerper, CY6 antikoerper, GPRCY6 antikoerper, TER1 antikoerper, C-C antikoerper, C-C CKR-8 antikoerper, CKR-8 antikoerper, Cmkbr8 antikoerper, mCCR8 antikoerper, C-C motif chemokine receptor 8 antikoerper, chemokine (C-C motif) receptor 8 antikoerper, CCR8 antikoerper, Ccr8 antikoerper

Hintergrund: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.

Cellular Localization: Cell membrane

Molekulargewicht: 41 kDa

Gen-ID: 1237