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CCR8 Antikörper (C-Term)

CCR8 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854720
  • Target Alle CCR8 Antikörper anzeigen
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    Bindungsspezifität
    • 14
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 50
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 42
    • 5
    • 4
    • 2
    • 1
    Kaninchen
    Klonalität
    • 45
    • 9
    Polyklonal
    Konjugat
    • 33
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCR8 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 28
    • 23
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit Polyclonal antibody to CCR8 (chemokine (C-C motif) receptor 8)
    CCR8 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CCR8. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: K562

    Validation: Orthogonal

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    Andere Bezeichnung
    C-C motif chemokine receptor 8 (CCR8 Produkte)
    Synonyme
    CC-CKR-8 antikoerper, CCR-8 antikoerper, CDw198 antikoerper, CKRL1 antikoerper, CMKBR8 antikoerper, CMKBRL2 antikoerper, CY6 antikoerper, GPRCY6 antikoerper, TER1 antikoerper, C-C antikoerper, C-C CKR-8 antikoerper, CKR-8 antikoerper, Cmkbr8 antikoerper, mCCR8 antikoerper, C-C motif chemokine receptor 8 antikoerper, chemokine (C-C motif) receptor 8 antikoerper, CCR8 antikoerper, Ccr8 antikoerper
    Hintergrund
    This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.

    Cellular Localization: Cell membrane
    Molekulargewicht
    41 kDa
    Gen-ID
    1237
    UniProt
    P51685
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