WT1 Antikörper (Center)
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- Target Alle WT1 Antikörper anzeigen
- WT1 (Wilms Tumor 1 (WT1))
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Bindungsspezifität
- Center
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WT1 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Produktmerkmale
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Rabbit Polyclonal antibody to Wilms Tumor 1 (Wilms tumor 1)
Wilms Tumor 1 antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Wilms Tumor 1. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product WT1 Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*
- Kommentare
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Positive Control: Mouse testis, Rat testis
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.11 mg/mL
- Buffer
- 1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- WT1 (Wilms Tumor 1 (WT1))
- Andere Bezeichnung
- Wilms Tumor 1 (WT1 Produkte)
- Synonyme
- AWT1 antikoerper, EWS-WT1 antikoerper, GUD antikoerper, NPHS4 antikoerper, WAGR antikoerper, WIT-2 antikoerper, WT33 antikoerper, CWT1 antikoerper, WT1 antikoerper, XWT1a antikoerper, wt-1 antikoerper, wt1 antikoerper, xWT1 antikoerper, WT-1 antikoerper, gud antikoerper, wagr antikoerper, wt33 antikoerper, xwt1 antikoerper, wit-2 antikoerper, si:ch211-160j6.3 antikoerper, zgc:152697 antikoerper, D630046I19Rik antikoerper, Wt-1 antikoerper, XWT1b antikoerper, XeWT1 antikoerper, Wilms tumor 1 antikoerper, Wilms tumor 1 S homeolog antikoerper, wilms tumor 1b antikoerper, Wilms tumor protein antikoerper, Wilms tumor 1 homolog antikoerper, Wilms tumor 1 L homeolog antikoerper, WT1 antikoerper, wt1.S antikoerper, wt1 antikoerper, wt1b antikoerper, Wt1 antikoerper, wt1.L antikoerper
- Hintergrund
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This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.
Cellular Localization: Nucleus - Molekulargewicht
- 49 kDa
- Gen-ID
- 7490
- Pathways
- Tube Formation
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