HEXIM1 Antikörper (Alexa Fluor 594)

Produktnummer ABIN2814312

Produktdetails anti-HEXIM1 Antikörper (Alexa Fluor 594)

Target: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HEXIM1 Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HEXIM1/EDG1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HEXIM1

Target: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Andere Bezeichnung: HEXIM1 (HEXIM1 Produkte)

Synonyme: HEXIM1 antikoerper, fd44h02 antikoerper, hexim antikoerper, wu:fd44h02 antikoerper, zgc:162976 antikoerper, CLP1 antikoerper, EDG1 antikoerper, HIS1 antikoerper, MAQ1 antikoerper, 7330426E13Rik antikoerper, CLP-1 antikoerper, Clp1 antikoerper, Clp-1 antikoerper, hexamethylene bisacetamide inducible 1 antikoerper, hexamethylene bis-acetamide inducible 1 antikoerper, hexamethylene bis-acetamide inducible 1 L homeolog antikoerper, HEXIM1 antikoerper, hexim1 antikoerper, Hexim1 antikoerper, hexim1.L antikoerper

Hintergrund:

Synonyms: Cardiac lineage protein 1, CLP 1, CLP1, EDG 1, EDG1, Estrogen down-regulated gene 1 protein, Hexamethylene bis acetamide inducible 1, Hexamethylene bis acetamide inducible protein, Hexamethylene bis acetamide inducible transcript 1, Hexamethylene bis-acetamide-inducible protein 1, HEXI1_HUMAN, HEXIM 1, Hexim1, HEXIM1 protein, HIS 1, HIS1, HMBA inducible, MAQ 1, MAQ1, Menage a quatre 1, Menage a quatre protein 1, Protein HEXIM1.

Background: Hexamethylene bis-acetamide inducible 1 (HEXIM1) and Hexamethylene bis-acetamide inducible 2 (HEXIM2) comprise a family of proteins which inhibit positive transcription elongation factor b (P-TEFb) through association with 7SK. P-TEFb is composed of a catalytic subunit, Cdk9, and either Cyclin T1 or T2 as a regulatory subunit. This complex regulates eukaryotic gene expression at the level of elongation. The C-terminal domains of HEXIM proteins interact directly with each other. Via these domains, HEXIM1 and HEXIM2 form stable homo- and hetero-oligomers, which may aid in the formation of the 7SK small nuclear ribonucleic acid particle. Despite their similar functions, HEXIM1 and HEXIM2 exhibit distinct expression patterns in various established cell lines and human tissues.

Gen-ID: 10614