HEXIM1 Antikörper

Produktnummer ABIN6262224

Produktdetails anti-HEXIM1 Antikörper

Target: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HEXIM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: HEXIM1 Antibody detects endogenous levels of HEXIM1

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HEXIM1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu HEXIM1

Target: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Andere Bezeichnung: HEXIM1 (HEXIM1 Produkte)

Synonyme: HEXIM1 antikoerper, fd44h02 antikoerper, hexim antikoerper, wu:fd44h02 antikoerper, zgc:162976 antikoerper, CLP1 antikoerper, EDG1 antikoerper, HIS1 antikoerper, MAQ1 antikoerper, 7330426E13Rik antikoerper, CLP-1 antikoerper, Clp1 antikoerper, Clp-1 antikoerper, hexamethylene bisacetamide inducible 1 antikoerper, hexamethylene bis-acetamide inducible 1 antikoerper, hexamethylene bis-acetamide inducible 1 L homeolog antikoerper, HEXIM1 antikoerper, hexim1 antikoerper, Hexim1 antikoerper, hexim1.L antikoerper

Hintergrund:

Description: Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor (PubMed:14580347, PubMed:15713661, PubMed:15201869). In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (PubMed:12832472, PubMed:14580347, PubMed:15713661, PubMed:15201869). May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity (PubMed:15940264, PubMed:15941832, PubMed:17088550). Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728).

Gene: HEXIM1

Molekulargewicht: 40kDa

Gen-ID: 10614

UniProt: O94992