TMEM43 Antikörper (Center)

Produktnummer ABIN2797836

Produktdetails anti-TMEM43 Antikörper

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Bindungsspezifität: AA 195-223, Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM43 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Verwendungszweck: Rabbit Anti-Human TMEM43 (Center) Antibody

Immunogen: This TMEM43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human TMEM43.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50TMEM43 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu TMEM43

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Andere Bezeichnung: TMEM43 (TMEM43 Produkte)

Synonyme: zgc:85946 antikoerper, ARVC5 antikoerper, ARVD5 antikoerper, EDMD7 antikoerper, LUMA antikoerper, 1200015A22Rik antikoerper, transmembrane protein 43 antikoerper, TMEM43 antikoerper, tmem43 antikoerper, Tmem43 antikoerper

Hintergrund:

Target Description: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Gene Symbol: TMEM43

Molekulargewicht: 44876 Da

Gen-ID: 79188

UniProt: Q9BTV4