TPX2 Antikörper (AA 350-382)

Produktnummer ABIN2796197

Produktdetails anti-TPX2 Antikörper

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Bindungsspezifität: AA 350-382

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Rabbit Anti-Human P100 Antibody

Immunogen: This P100 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-382 amino acids from human P100.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100The anti-p100 Pab is used in Western blot to detect p100 in placenta lysate.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.0 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu TPX2

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Andere Bezeichnung: P100 (TPX2 Produkte)

Synonyme: C20orf1 antikoerper, C20orf2 antikoerper, DIL-2 antikoerper, DIL2 antikoerper, FLS353 antikoerper, GD:C20orf1 antikoerper, HCA519 antikoerper, HCTP4 antikoerper, REPP86 antikoerper, p100 antikoerper, 2610005B21Rik antikoerper, TPX2 antikoerper, dil-2 antikoerper, dil2 antikoerper, hctp4 antikoerper, repp86 antikoerper, tpx2 antikoerper, TPX2, microtubule nucleation factor antikoerper, TPX2, microtubule-associated antikoerper, TPX2, microtubule-associated, homolog (Xenopus laevis) antikoerper, TPX2, microtubule-associated S homeolog antikoerper, TPX2, microtubule-associated L homeolog antikoerper, TPX2 antikoerper, Tpx2 antikoerper, tpx2.S antikoerper, tpx2.L antikoerper

Hintergrund:

Target Description: The nuclear protein p100 is a proliferation-associated protein whose expression is restricted to cell cycle phases S, G2, and M. Exclusively expressed in proliferating cells from the transition G1/S until the end of cytokinesis. During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. The full-length cDNA encodes a 747-amino acid protein with a putative ATP/GTP-binding site motif. RT-PCR analysis demonstrated strong expression of in lung carcinoma cell lines but not in normal lung tissues. Expression was also found in adult placenta, skeletal muscle, thymus, testis, and small intestine and in fetal brain, liver, and kidney. P100 is also correlated to cancer prognosis.

Gene Symbol: TPX2

Molekulargewicht: 85653 Da

Gen-ID: 22974

UniProt: Q9ULW0