TPX2 Antikörper (Internal Region)
Kurzübersicht für TPX2 Antikörper (Internal Region) (ABIN784231)
Target
Alle TPX2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- This aAntibody detects endogenous levels of total TPX2 protein.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
Aufreinigung
- Immunoaffinity Chromatography.
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Immunogen
- Synthetic peptide - KLH conjugated Remarks: Antigen Modification: Internal
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
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Andere Bezeichnung
- TPX2 / DIL2
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Hintergrund
- TPX2 is a spindle assembly factor, required for normal assembly of mitotic spindles, for normal assembly of microtubules during apoptosis, and for chromatin and/or kinetochore dependent microtubule nucleation. TPX2 mediates AURKA localization to spindle microtubules, activates AURKA by promoting its autophosphorylation at 'Thr-288', and protects this residue against dephosphorylation.Synonyms: C20orf1, C20orf2, DIL-2, Differentially expressed in cancerous and non-cancerous lung cells 2, HCA519, Hepatocellular carcinoma-associated antigen 519, Restricted expression proliferation-associated protein 100, Targeting protein for Xklp2
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Gen-ID
- 22974
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NCBI Accession
- NP_036244
Target
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