PCDHGB4 Antikörper (Center)

Produktnummer ABIN2795510

Produktdetails anti-PCDHGB4 Antikörper

Target: PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))

Bindungsspezifität: AA 353-379, Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHGB4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit Anti-Human PCDHGB4 (Center) Antibody

Immunogen: This PCDHGB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-379 amino acids from the Central region of human PCDHGB4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000PCDHGB4 Antibody (Center).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.300 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu PCDHGB4

Target: PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))

Andere Bezeichnung: PCDHGB4 (PCDHGB4 Produkte)

Synonyme: CDH20 antikoerper, FIB2 antikoerper, PCDH-GAMMA-B4 antikoerper, protocadherin gamma subfamily B, 4 antikoerper, PCDHGB4 antikoerper, Pcdhgb4 antikoerper

Hintergrund:

Target Description: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This particular family member is expressed in fibroblasts and is thought to play a role in wound healing in response to injury. Alternative splicing has been described for the gamma cluster genes.

Gene Symbol: PCDHGB4

Molekulargewicht: 99927 Da

Gen-ID: 8641

UniProt: Q9UN71