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PCDHGB4 Antikörper (AA 353-379)

PCDHGB4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB39608 unconjugated
Produktnummer ABIN1538347
  • Target Alle PCDHGB4 Antikörper anzeigen
    PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 1
    • 1
    AA 353-379
    Reaktivität
    Human
    Wirt
    • 14
    • 1
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser PCDHGB4 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 14
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PCDHGB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-379 amino acids from the Central region of human PCDHGB4.
    Klon
    RB39608
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    PCDHGB4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))
    Andere Bezeichnung
    PCDHGB4 (PCDHGB4 Produkte)
    Synonyme
    CDH20 antikoerper, FIB2 antikoerper, PCDH-GAMMA-B4 antikoerper, protocadherin gamma subfamily B, 4 antikoerper, PCDHGB4 antikoerper, Pcdhgb4 antikoerper
    Hintergrund
    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This particular family member is expressed in fibroblasts and is thought to play a role in wound healing in response to injury. Alternative splicing has been described for the gamma cluster genes.
    Molekulargewicht
    99927
    Gen-ID
    8641
    NCBI Accession
    NP_003727, NP_115269
    UniProt
    Q9UN71
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