KDELR2 Antikörper (Middle Region)
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- Target Alle KDELR2 Antikörper anzeigen
- KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KDELR2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PVGGLSFLVN HDFSPLEYSR ERSSVCQHKC QRPSPASVLQ GARTEFLPQQ
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against KDELR2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human KDELR2
- Top Product
- Discover our top product KDELR2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 186 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
- Andere Bezeichnung
- KDELR2 (KDELR2 Produkte)
- Synonyme
- kdelr2 antikoerper, ELP-1 antikoerper, ERD2.2 antikoerper, 1110007A14Rik antikoerper, kdelr1-a antikoerper, KDEL endoplasmic reticulum protein retention receptor 2 L homeolog antikoerper, KDEL endoplasmic reticulum protein retention receptor 2 antikoerper, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 antikoerper, KDEL endoplasmic reticulum protein retention receptor 1 L homeolog antikoerper, kdelr2.L antikoerper, KDELR2 antikoerper, Kdelr2 antikoerper, kdelr1.L antikoerper
- Hintergrund
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Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83 % identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: ELP-1, ERD2.2
Protein Interaction Partner: UBC, ELAVL1, SERINC3,
Protein Size: 186 - Molekulargewicht
- 21 kDa
- Gen-ID
- 11014
- NCBI Accession
- NM_001100603, NP_001094073
- UniProt
- P33947
- Pathways
- Maintenance of Protein Location
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